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ASN NEURO (2009) 1(2):art:e00009.doi:10.1042/AN20090002

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Brain injury expands the numbers of neural stem cells and progenitors in the SVZ by enhancing their responsiveness to EGF

Dhivyaa Alagappan*, Deborah A Lazzarino*, Ryan J Felling*, Murugabaskar Balan†, Sergei V Kotenko† and Steven W Levison*¹

^*Department of Neurology and Neuroscience, UMDNJ-New Jersey Medical School, Newark, NJ 07103, U.S.A.
^†Department of Biochemistry and Molecular Biology, UMDNJ-New Jersey Medical School, Newark, NJ 07103, U.S.A.

¹To whom correspondence should be addressed (email steve.levison@umdnj.edu).

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SUPPLEMENTARY DATA

Figure S1 Expression of EGFR ligands during recovery from neonatal H/I

(A) Real-time PCR using primers specific for EGFR ligands, EGF, HB-EGF and TGF-α and normalized to expression of 18S after 72 h recovery. (B) Real-time PCR using primers specific for TGF-α and normalized to expression of 18S after 72 h and 7 day recovery. n = 6 for ipsilateral, contralateral and control. *P<0.05, as measured using REST.

Received 20 January 2009/13 April 2009; accepted 17 April 2009

Published as ASN NEURO Immediate Publication 17 April 2009, doi:10.1042/AN20090002

©2009 The Author(s) This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial Licence (http://creativecommons.org/licenses/by-nc/2.5/) which permits unrestricted non-commercial use, distribution and reproduction in any medium, provided the original work is properly cited.